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Two possible roles have been suggested: biotransformation of electrophilic compounds, protecting the DNA content, where the GST catalyzes the conjugation of glutathione to the xenobiotic compound in a detoxification-related mechanism, and a possible role in modulating gene expression

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IGF-1 LR3 has been discussed in scientific literature involving insulin-like growth factor research, peptide receptor biology, molecular signaling pathways, protein interactions, cellular communication, and controlled laboratory models

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